5 edition of Molecular Diagnostics of Human Cancer (Cancer Cells, No. 7) (Cancer Cells, No. 7) found in the catalog.
November 1, 1989
by Cold Spring Harbor Laboratory Pr
Written in English
|Contributions||Melvyn Greaves (Editor)|
|The Physical Object|
|Number of Pages||414|
The pharmaceutical industry is still struggling to cure cancer despite pouring enormous resources into the search for new treatments. We take a look at the some of the current technologies for the discovery and delivery of molecular diagnostic, prognostic and predictive tests and speculate on where this area is heading with regard to advanced technologies and likely future requirements. Molecular Diagnostics in Breast Cancer Routine Practice This study involves a review of the literature and did not involve any studies with human or animal subjects performed by any of the authors. No funding was received for the publication of this article.
This book covers the concepts of molecular medicine and personalized medicine. Subsequent chapters cover the topics of genomics, transcriptomics, epigenomics, and proteomics, as the tools of molecular pathology and foundations of molecular medicine. These chapters are followed by a series of. Molecular Diagnostics: The Key in Personalized Cancer Medicine Content This unique book provides a thorough overview of developing molecular cancer diagnostic assays, which are the prerequisites for optimal solutions within personalized cancer medicine. The book takes the reader through definitions of the pharmacodiagnostic concept, historical perspectives of the early steps into molecular.
The 2e of Molecular Diagnostics, the only book dealing with diagnosis on a molecular level, discusses current molecular biological techniques used to identify the underlying molecular defects in inherited book delves further into the principle and brief description of the technique, followed by examples from the authors' own expertise. Introduction. Molecular diagnostics is a part of laboratory medicine, which relies on the detection of individual biologic molecules. The potential of molecular genetic tools was initially recognized by oncohematologists, given that specific chromosomal translocations may significantly aid the diagnosis of various leukemias and lymphomas (Fey and Wainscoat, ).
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This book aims to bring together a broad variety of examples of the role of pharmacogenomics in current drug development, uncovering dynamic concentration-dependent drug responses on biological systems to understand pharmacodynamics responses in human cancer where genetic lesions serve as tumor markers and provide a basis for cancer diagnosis.
The book describes methods and protocols applied in molecular diagnostics. The Molecular Basis of Human Cancer, Second Edition, is a valuable resource for oncologists, researchers, and all medical professionals who work with cancer.
Molecular diagnostics of human cancer. [Cold Spring Harbor, N.Y.]: Cold Spring Harbor Laboratory Press: May be ordered from Cold Spring Harbor Laboratory, (OCoLC) Online version: Molecular diagnostics of human cancer.
This book aims to bring together a broad variety of examples of the role of pharmacogenomics in current drug development, uncovering dynamic concentration-dependent drug responses on biological.
Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing is organized around disease types (genetic disease, infectious disease, neoplastic disease, among others). In each section, the authors provide background on disease mechanisms and describe how laboratory testing is built on knowledge of these mechanisms.5/5(3).
The book takes the reader through definitions of the pharmacodiagnostic concept, historical perspectives of the early steps into molecular cancer diagnostics linked to therapy, the basis of different diagnostic molecular techniques, ongoing research, drug-diagnostic co-development, assay validation, clinical trial methodology, regulatory issues around pharmacodiagnostics and future aspects within personalized cancer medicine.
Description Molecular Diagnostics, Third Edition, focuses on the technologies and applications that professionals need to work in, develop, and manage a clinical diagnostic laboratory.
Molecular Diagnostics and Treatment of Pancreatic Cancer describes the different emerging applications of systems biology and how it is shaping modern pancreatic cancer research.
This book begins by introducing the current state of the art knowledge, trends in diagnostics, progress in disease model systems as well as new treatment and palliative care strategies in pancreatic cancer. Cumpără cartea The Molecular Basis of Human Cancer de William B.
Coleman la prețul de lei, discount 5% cu livrare gratuită prin curier oriunde în România. Human papillomavirus (HPV) is the most common sexually transmitted infection in the United States, affecting men and women.
1 It is estimated that more than 24 million men and women in the United States are currently infected with HPV. 2, 3 More than 4 million new HPV infections are reported in the United States annually, and about 1%–10% of the sexually active U.S.
population is infected at. By integrating technology, supporting infrastructure and efficient application, the all-in-one guide presents molecular diagnostics as an essential component of modern, personalized clinical practice.
It considers all important aspects, from the hardware and software needed, to recent improvements in blood- and non-blood-based biomarker tests. This book aims to bring together a broad variety of examples of the role of pharmacogenomics in current drug development, uncovering dynamic concentration-dependent drug responses on biological systems to understand pharmacodynamics responses in human cancer where genetic lesions serve as tumor markers and provide a basis for cancer diagnosis.
Book description. Advances in Cell and Molecular Diagnostics brings the scientific advances in the translation and validation of cellular and molecular discoveries in. Applications of Molecular Diagnostics for Human Cancers Molecular Pathogenesis of Human Cancer William B.
Coleman and Gregory J. Tsongalis This slim yet weighty book is the second edition of a comprehensive review of molecular diagnostic testing in the clinical : $ Cancer is a disease of the genome, arising from DNA alterations that dysregulate gene structure or function.
Unraveling the pathogenesis of cancer has not only helped to understand how a cell transforms into a tumor but has also promoted molecular tests that now help diagnose and provide prognoses for a variety of cancers in humans and animals.
Molecular diagnostics are increasingly used to guide patient management, from diagnosis to treatment, particularly in the fields of cancer, infectious disease, and congenital abnormalities. The increased demand for genetic and genomic information has led to the rapid expansion of molecular techniques within clinical laboratories.
Part II of the book presents a broad, but exemplary selection of cancers that serve as paradigms to illustrate this point. In fact, cancer research has now reached a critical stage, in which the accumulated knowledge on molecular mechanisms is gradually translated into improved prevention, diagnosis.
Part VII. Applications of Molecular Diagnostics for Human Cancers. Molecular Pathogenesis of Human Cancer. William B. Coleman and Gregory J. Tsongalis. Application of Molecular Diagnostics to Hereditary Nonpolyposis Colorectal Cancer.
Ian M. Frayling, Lisa Happerfield, Christopher Mattocks, Kim Oakhill, and Mark J. Arends. the molecular features of breast cancer may potentially provide additional diagnostic, prognostic and predictive information that may, in the not so distant future, facilitate the development of.
Molecular diagnostics have already improved cancer diagnosis and treatment techniques, and research is continuing. The image above shows the many areas in which molecular diagnostics could be used. This spans the entire scope of cancer care beginning with risk assessment and moving through to surveillance after diagnosis and treatment.
Meet the challenges of this rapidly expanding field with a solid understanding of the fundamentals of nucleic acid biochemistry as well as the advanced concepts integral to practice in today’s laboratories. With a focus on the application of molecular concepts to the diagnosis of disease, the 3rd Edition of this popular resource encompasses microbiology, virology, genetics, oncology, and.In I coedited a book, Molecular Pathology: Ap- efforts.
It should be evident that molecular pathology and proaches to Diagnosing Human Disease in the Clinical diagnostics impact almost every conceivable subspecialty Laboratory, that coined the phrase “molecular pathology” in laboratory medicine and, particularly in the case of to refer to applications of molecular biology in the tradi.
• The molecular basis of therapy—including critical molecules as special treatment targets, particularly genes/DNA, RNA, micro RNAs, proteins/antibodies, and nanoparticles. • Molecular diagnostics – including updated molecular diagnostic approaches to common malignancies and role of pathology in targeted cancer management.